Preoperative Evaluation of Living Related Kidney Donor: Which Kidney to Donate?

• Published in: Transplantation proceedings Vol. 38; no. 7; pp. 1980 - 1981
• Main Authors: Wu, C.-T., Liu, K.-L., Chu, S.-H., Chiang, Y.-J.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: New York, NY Elsevier Inc 01.09.2006; Elsevier Science
• Subjects: Adult; Biological and medical sciences; Family; Female; Functional Laterality; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Graft Survival - physiology; Humans; Kidney; Kidney Function Tests; Kidney Transplantation - physiology; Laparoscopy; Living Donors; Male; Medical sciences; Middle Aged; Nephrectomy; Preoperative Care; Retrospective Studies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tissue and Organ Harvesting; Tissue, organ and graft immunology; Medicine; Evaluation; Treatment; Urinary system; Surgery; Living donor; Related donor; Homograft; Graft; Transplantation; Preoperative; Kidney
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2006.06.110

As the number of cadaveric donor is far beyond the demand of the waiting list, living related kidney transplantation is important for the worldwide organ shortage. Besides, living related transplantation has advantages compared with cadaveric transplantation in terms of graft function and survival. However, the remaining kidney function of the living donor needs to be evaluated. We collected 28 paired living kidney donations from March 2003 to March 2005. All patients underwent laparoscopic donor nephrectomy. The preoperative kidney evaluation included renal echography, renal nuclear scan, computed tomography angiography (CTA), and creatinine clearance (CCr). The renal function of the donor kidney was expressed as (donor kidney/both kidneys)%. The percentage renal function from renal echography, renal nuclear scan, and CTA were correlated with CCr. The mean percentage of donor kidney function according to renal echo, nuclear scan, and CTA were 49.77%, 51.83%, and 50.70%, respectively. The correlation coefficients for renal echography, nuclear scan, and CTA to CCr were −0.316, −0.201, and 0.123, respectively. The correlation coefficients for renal echography, nuclear scan, and CTA to postoperative serum creatinine of donor were 0.426, 0.036, and −0.119, respectively. From the viewpoint of donor postoperative residual renal function, preoperative renal sonography offered a better predictive value than nuclear scan or CTA.