A distinct splice form of APC is highly expressed in neurones but not commonly mutated in neuroepithelial tumours

• Published in: Journal of medical genetics Vol. 38; no. 4; pp. 257 - 262
• Main Authors: STEIGERWALD, Kira, SANTORO, Irma M, LOWY, Andrew M, VARESCO, Liliana, GRODEN, Joanna, KORDICH, Jennifer J, GISMONDI, Viviana, TRZEPACZ, Chris, BADIALI, Manuela, GIANGASPERO, F, BALKO, M. Gregory, GRAHAM, Jennifer S, RATNER, Nancy
• Format: Journal Article
• Language: English
• Published: London BMJ 01.04.2001; BMJ Group
• Subjects: Adenomatous Polyposis Coli Protein; Alternative Splicing; Animals; Biological and medical sciences; Cells, Cultured; Cerebellum - cytology; Cerebellum - metabolism; Cytoskeletal Proteins - genetics; DNA - chemistry; DNA - genetics; DNA Mutational Analysis; Gene Expression; Glioblastoma - genetics; Glioblastoma - pathology; Humans; Letters to the Editor; Medical sciences; Medulloblastoma - genetics; Medulloblastoma - pathology; Mutation; Neoplasms, Neuroepithelial - genetics; Neoplasms, Neuroepithelial - pathology; Neurology; Neurons - cytology; Neurons - metabolism; Polymorphism, Single-Stranded Conformational; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA - genetics; RNA - metabolism; Spinal Cord - cytology; Spinal Cord - embryology; Spinal Cord - metabolism; Tumor Cells, Cultured; Tumors of the nervous system. Phacomatoses; Human; Nervous system diseases; Spinal cord; Neuroepithelioma; Rat; Transcription; Pathogenesis; Rodentia; Glioblastoma; Malignant tumor; Gene expression; Genetic determinism; Malignant glioma; Vertebrata; Mammalia; Neuron; Blastoma; Animal; Central nervous system disease; Risk factor; Mutation; Spinal cord disease; Tumor suppressor gene
• ISSN: 0022-2593; 1468-6244; 1468-6244
• DOI: 10.1136/jmg.38.4.257