Role of Mechanical Loading for Platelet-Rich Plasma-Treated Achilles Tendinopathy

There is no consensus on the optimal rehabilitation protocol after platelet-rich plasma (PRP) treatment for tendinopathy despite basic science studies showing the critical role of mechanical loading in the restoration of tendon structure and function posttreatment. In this article, we will review te...

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Bibliographic Details
Published inCurrent sports medicine reports Vol. 19; no. 6; pp. 209 - 216
Main Authors Neph, Alyssa, Schroeder, Allison, Enseki, Keelen R, Everts, Peter A, Wang, James H-C, Onishi, Kentaro
Format Journal Article
LanguageEnglish
Published United States 01.06.2020
Subjects
Achilles Tendon - injuries
Animals
Combined Modality Therapy
Exercise Therapy - methods
Humans
Platelet-Rich Plasma
Tendinopathy - therapy
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Summary:There is no consensus on the optimal rehabilitation protocol after platelet-rich plasma (PRP) treatment for tendinopathy despite basic science studies showing the critical role of mechanical loading in the restoration of tendon structure and function posttreatment. In this article, we will review tendon mechanobiology, platelet biology, and review levels I and II Achilles tendon clinical studies paying particular attention to the role of mechanical loading in rehabilitation of injured tendons. Animal studies emphasize the synergistic effect of mechanical tendon loading and PRP to treat tendon injury while clinical studies described minimal details on loading protocols.
Bibliography:ObjectType-Article-2
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ISSN:1537-8918
1537-890X
1537-8918
DOI:10.1249/JSR.0000000000000719