Resolution of fetal second-degree atrioventricular block

Fetal atrioventricular (AV) block is a rare and potentially devastating condition. Most commonly fetal AV block is mediated by maternal lupus antibodies which cause irreversible damage to the AV node. For many fetuses, the only potential intervention is premature delivery and highly invasive pacemak...

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Bibliographic Details
Published inJournal of electrocardiology Vol. 51; no. 6; pp. 945 - 947
Main Authors Newbury, Alex, Fahey, Michael
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.11.2018
Elsevier Science Ltd
Subjects
Anti-Ro/anti-La
Congenital AV heart block
Congenital maternal Lupus
Immunoglobulins
Intervention
Medical diagnosis
Neonate
Ultrasonic imaging
Anti-Ro/anti-La
Congenital AV heart block
Neonate
Congenital maternal Lupus
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Summary:Fetal atrioventricular (AV) block is a rare and potentially devastating condition. Most commonly fetal AV block is mediated by maternal lupus antibodies which cause irreversible damage to the AV node. For many fetuses, the only potential intervention is premature delivery and highly invasive pacemaker implantation. However, there exists a small subset of fetuses with non-immune mediated AV block who appear to have far better outcomes, with potential for spontaneous resolution and a return to sinus rhythm. Despite this, it is not clear that prenatal counseling takes this fact into account. We describe a series of three patients with non-immune fetal second-degree AV block with spontaneous resolution prior to delivery, underscoring the need for appropriate prenatal counseling in this scenario.
Bibliography:ObjectType-Case Study-2
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ISSN:0022-0736
1532-8430
DOI:10.1016/j.jelectrocard.2018.08.020