FIZICS: fluorescent imaging zone identification system, a novel macro imaging system

Constantly improving biological assay development continues to drive technological requirements. Recently, a specification was defined for capturing white light and fluorescent images of agar plates ranging in size from the NUNC Omni tray (96-well footprint, 128 x 85 mm) to the NUNC Bio Assay Dish (...

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Bibliographic Details
Published inJournal of biomolecular screening Vol. 9; no. 8; pp. 663 - 670
Main Authors Skwish, Stephen, Asensio, Francisco, King, Greg, Clarke, Glenn, Kath, Gary, Salvatore, Michael J, Dufresne, Claude
Format Journal Article
LanguageEnglish
Published United States 01.12.2004
Subjects
Biological Assay - instrumentation
Image Processing, Computer-Assisted - instrumentation
Microscopy, Fluorescence - instrumentation
Software
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Summary:Constantly improving biological assay development continues to drive technological requirements. Recently, a specification was defined for capturing white light and fluorescent images of agar plates ranging in size from the NUNC Omni tray (96-well footprint, 128 x 85 mm) to the NUNC Bio Assay Dish (245 x 245 mm). An evaluation of commercially available products failed to identify any system capable of fluorescent macroimaging with discrete wavelength selection. To address the lack of a commercially available system, a custom imaging system was designed and constructed. This system provides the same capabilities of many commercially available systems with the added ability to fluorescently image up to a 245 x 245 mm area using wavelengths in the visible light spectrum.
ISSN:1087-0571
2472-5552
DOI:10.1177/1087057104265289