Turn up the HEAT

The recently determined crystal structure of the PR65/A subunit of protein phosphatase 2A reveals the architecture of proteins containing HEAT repeats. The structural properties of this solenoid protein explain many functional characteristics and account for the involvement of solenoids as scaffold,...

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Bibliographic Details
Published inStructure Vol. 7; no. 5; pp. R91 - R97
Main Authors Kobe, Bostjan, Gleichmann, Thomas, Horne, James, Jennings, Ian G, Scotney, Pierre D, Teh, Trazel
Format Book Review Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.05.1999
Subjects
biochemistry
Phosphoprotein Phosphatases - chemistry
Protein Conformation
Protein Phosphatase 2
structural biology
structural biology
biochemistry
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Summary:The recently determined crystal structure of the PR65/A subunit of protein phosphatase 2A reveals the architecture of proteins containing HEAT repeats. The structural properties of this solenoid protein explain many functional characteristics and account for the involvement of solenoids as scaffold, anchoring and adaptor proteins.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0969-2126
1878-4186
DOI:10.1016/S0969-2126(99)80060-4