Impact of Mechanical Circulatory Support on Posttransplant Outcomes

Mechanical circulatory support (MCS) has markedly improved the likelihood of transplant among patients with advanced heart failure. Transplant survival following MCS is similar for supported and unsupported recipients. Transplant survival is only reduced following left ventricle assist device (LVAD)...

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Bibliographic Details
Published inCardiology clinics Vol. 36; no. 4; p. 551
Main Author Dardas, Todd F
Format Journal Article
LanguageEnglish
Published Netherlands 01.11.2018
Subjects
Delayed Graft Function - surgery
Heart Failure - surgery
Heart Transplantation
Heart-Assist Devices
Humans
Postoperative Care - instrumentation
Treatment Outcome
Artificial heart
Health utility
Heart transplant
Mechanical circulatory support
Temporary circulatory support
Survival
Risk factors
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Summary:Mechanical circulatory support (MCS) has markedly improved the likelihood of transplant among patients with advanced heart failure. Transplant survival following MCS is similar for supported and unsupported recipients. Transplant survival is only reduced following left ventricle assist device (LVAD) support complicated by infection, total artificial heart support, and extracorporeal life support. Despite allosensitization and a higher incidence of vasoplegia syndrome, posttransplant survival for durable LVADs is similar to patients with inotropes alone at the time of transplant. MCS as a bridge to transplant offers significant benefits over waiting without support.
ISSN:1558-2264
DOI:10.1016/j.ccl.2018.06.009