Update on primary cutaneous T-cell lymphomas rare subtypes

Rare subtypes of cutaneous T-cell lymphomas (CTCL) include four entities, primary cutaneous γδ T-cell lymphoma, primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma, and primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorders, primary cutaneous acral CD8+ T-cel...

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Published inDermatology reports Vol. 16; no. Suppl 2; p. 9961
Main Authors Alberti-Violetti, Silvia, Berti, Emilio
Format Journal Article
LanguageEnglish
Published Italy PAGEPress Publications, Pavia, Italy 07.05.2024
PAGEPress Publications
Subjects
aggressive lymphoma
Cutaneous lymphoma
rare cutaneous lymphoma
Review
T follicular helper phenotype
aggressive lymphoma
rare cutaneous lymphoma
T follicular helper phenotype
cutaneous lymphoma
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Summary:Rare subtypes of cutaneous T-cell lymphomas (CTCL) include four entities, primary cutaneous γδ T-cell lymphoma, primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma, and primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorders, primary cutaneous acral CD8+ T-cell lymphoma, which were previously considered provisional and are now included in the new 5 World Health Organization classification of hematolymphoid tumors as distinct entities. An updated summary of the clinical, histological, and genomic characteristics of these uncommon CTCL subtypes is given in this review, with a focus on the growing body of knowledge regarding their classification and possible treatment strategies.
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Consent for publication: the patients gave their consent for the publication of this article and any accompanying images.
Conflict of interest: the authors declare no conflict of interest.
Publisher's note: all claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
ISSN:2036-7392
2036-7406
DOI:10.4081/dr.2024.9961