Hijacking a Morphogenesis Proteinase for Cancer Cell Invasion

A long-standing question in biology is whether cancer cells exploit developmental processes to invade the surrounding stroma. In this issue of Developmental Cell, Feinberg et al. (2018) identify the matrix metalloproteinase Mmp14 as a key driver of mammary invasion common to both development and can...

Full description

Saved in:
Bibliographic Details
Published inDevelopmental cell Vol. 47; no. 2; pp. 135 - 137
Main Author Akhtar, Nasreen
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 22.10.2018
Subjects
Breast
Epithelial Cells
Humans
Matrix Metalloproteinase 14
Morphogenesis
Neoplasm Invasiveness
Proteolysis
Online AccessGet full text

Cover

More Information
Summary:A long-standing question in biology is whether cancer cells exploit developmental processes to invade the surrounding stroma. In this issue of Developmental Cell, Feinberg et al. (2018) identify the matrix metalloproteinase Mmp14 as a key driver of mammary invasion common to both development and cancer but expose an underlying twist. A long-standing question in biology is whether cancer cells exploit developmental processes to invade the surrounding stroma. In this issue of Developmental Cell, Feinberg et al. (2018) identify the matrix metalloproteinase Mmp14 as a key driver of mammary invasion common to both development and cancer but expose an underlying twist.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Commentary-1
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2018.10.007