Any Future for Faecal Microbiota Transplantation as a Novel Strategy for Gut Microbiota Modulation in Human and Veterinary Medicine?

• Published in: Life (Basel, Switzerland) Vol. 12; no. 5; p. 723
• Main Authors: Takáčová, Martina, Bomba, Alojz, Tóthová, Csilla, Micháľová, Alena, Turňa, Hana
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 12.05.2022; MDPI
• Subjects: Animals; Antibiotics; Antimicrobial agents; Bacteria; Bile; Carbohydrates; Chronic illnesses; Colon; Diarrhea; Diet; Digestive system; Digestive tract; dogs; Dysbacteriosis; faecal microbiota transplantation; Gastrointestinal diseases; gut; Immune system; Intestinal microflora; Intestine; Medicine; Metabolism; Metabolites; microbiome; Microbiomes; Microbiota; Modulation; Motility; Permeability; Probiotics; Recurrent infection; Review; Transplantation; Veterinary medicine; dogs; faecal microbiota transplantation; modulation; microbiome; gut; probiotics
• ISSN: 2075-1729; 2075-1729
• DOI: 10.3390/life12050723

Alterations in the composition of the intestinal microbiome, also known as dysbiosis, are the result of many factors such as diet, antibiotics, stress, diseases, etc. There are currently several ways to modulate intestinal microbiome such as dietary modulation, the use of antimicrobials, prebiotics, probiotics, postbiotics, and synbiotics. Faecal microbiota transplantation (FMT) represents one new method of gut microbiota modulation in humans with the aim of reconstructing the intestinal microbiome of the recipient. In human medicine, this form of bacteriotherapy is successfully used in cases of recurrent infection (CDI). FMT has been known in large animal medicine for several years. In small animal medicine, the use of FMT is not part of normal practice.