How I treat patients with systemic sclerosis in clinical practice

Systemic sclerosis (SSc) or scleroderma is a disorder of the connective tissue affecting the skin, and it is often associated with visceral involvement. The predominant pathological features of SSc are autoimmunity, vasculopathy, and fibrosis. Progressive fibrosis is associated with changes in the m...

Full description

Saved in:
Bibliographic Details
Published inAutoimmunity reviews Vol. 16; no. 10; pp. 1024 - 1028
Main Authors Rossi, Daniela, Zanatta, Elisabetta, Marson, Piero, Sciascia, Savino, Polito, Pamela, Roccatello, Dario, Cozzi, Franco
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.10.2017
Subjects
Humans
Scleroderma, Systemic - immunology
Scleroderma, Systemic - therapy
Online AccessGet full text

Cover

More Information
Summary:Systemic sclerosis (SSc) or scleroderma is a disorder of the connective tissue affecting the skin, and it is often associated with visceral involvement. The predominant pathological features of SSc are autoimmunity, vasculopathy, and fibrosis. Progressive fibrosis is associated with changes in the microcirculation of the involved organs. Here, we review the clinical features of systemic sclerosis and describe the best practice approaches for its management, reviewing available guidelines and recommendations and providing experts' insights.
ISSN:1568-9972
1568-9972
1873-0183
DOI:10.1016/j.autrev.2017.07.018