Towards a molecular understanding of arthritis

Several different agents including free radicals, oxidizing compounds and proteases are believed to play a role in the onset of arthritis. The evidence and underlying chemistry presently available for each destructive agent are presented.

Saved in:
Bibliographic Details
Published inChemistry & biology Vol. 6; no. 6; pp. R157 - R166
Main Authors Flugge, Lisa A, Miller-Deist, Lynne A, Petillo, Peter A
Format Journal Article
LanguageEnglish
Published United States Elsevier Ltd 01.06.1999
Subjects
Aggrecans
Arthritis - etiology
Arthritis - metabolism
Carbohydrate Sequence
Cartilage - metabolism
Extracellular Matrix Proteins
Free Radicals - metabolism
Humans
Hyaluronic Acid - chemistry
Hyaluronic Acid - metabolism
Lectins, C-Type
Metalloendopeptidases - metabolism
Molecular Sequence Data
Nitric Oxide - metabolism
Proteoglycans - chemistry
Proteoglycans - metabolism
Online AccessGet full text

Cover

More Information
Summary:Several different agents including free radicals, oxidizing compounds and proteases are believed to play a role in the onset of arthritis. The evidence and underlying chemistry presently available for each destructive agent are presented.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1074-5521
1879-1301
DOI:10.1016/S1074-5521(99)80043-X