Prolonged Continuous Theta-burst Stimulation is More Analgesic Than ‘Classical’ High Frequency Repetitive Transcranial Magnetic Stimulation

• Published in: Brain stimulation Vol. 8; no. 1; pp. 135 - 141
• Main Authors: Moisset, Xavier, Goudeau, Simon, Poindessous-Jazat, Frédérique, Baudic, Sophie, Clavelou, Pierre, Bouhassira, Didier
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 2015
• Subjects: Adult; Analgesia - methods; Conditioned pain modulation; Cortical excitability; Evoked Potentials, Motor - physiology; Female; Humans; Male; Motor Cortex - physiology; Neural Inhibition - physiology; Neurology; Pain; Pain Threshold; Repetitive transcranial magnetic stimulation; Theta Rhythm; Thêta-burst stimulation; Time Factors; Transcranial Magnetic Stimulation - methods; Cortical excitability; Thêta-burst stimulation; Repetitive transcranial magnetic stimulation; Pain; Conditioned pain modulation

Abstract Background Repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex (M1) at high frequency (>5 Hz) induces analgesic effects, probably by activating pain modulation systems. A new rTMS paradigm – theta burst stimulation (TBS) – consists of bursts of three pulses at...