Analysis of Placental Vascularization by Means of 3D Power Doppler in Women Pregnant Following Oocyte Donation

• Published in: Reproductive sciences (Thousand Oaks, Calif.) Vol. 17; no. 8; pp. 754 - 759
• Main Authors: Sellers López, F., Orozco-Beltran, Domingo, Gil-Guillen, Vicente, Lozano, J.M., Palacios, A., Bernabeu, R.
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.08.2010; Springer International Publishing; Sage Publications
• Subjects: Adult; Biological and medical sciences; Cardiovascular system; Embryology; Female; Gynecology. Andrology. Obstetrics; Humans; Imaging, Three-Dimensional; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Medicine & Public Health; Middle Aged; Obstetrics/Perinatology/Midwifery; Oocyte Donation - adverse effects; Original Article; Placenta - blood supply; Placenta - diagnostic imaging; Placental Circulation; Pregnancy; Pregnancy Trimester, Second; Reproductive Medicine; Ultrasonic investigative techniques; Ultrasonography, Doppler, Color; Ultrasonography, Prenatal - methods; recipient; placental vascularization; 3D Power Doppler; Oocyte donation; Sonography; Doppler ultrasound study; Human; Gynecology; Recipient; Obstetrics; Vascularization; Pregnancy; Placenta; Donation; Female; Woman; Oocyte
• ISSN: 1933-7191; 1933-7205
• DOI: 10.1177/1933719110371013

Objective: To analyze the differences in placental perfusion in pregnancies following oocyte donation compared to spontaneous pregnancies. Participants and Methods: A total of 33 patients who became pregnant after oocyte donation are studied and compared to 42 spontaneously pregnant participants. A 3-dimensional Power Doppler is used to obtain 3 placental volumes. Of each volume, 3 portions are analyzed in the form of a spherical ‘‘placental biopsy.’’ Four vascularization rates are applied, using the virtual organ computer-aided analysis (VOCAL) method: grey index (GI), vascularization index (VI), flow index (FI), and vascularization-flow index (VFI). Results: Vascular alterations are demonstrated, manifested by a lower IG and a significantly higher IV in the group of spontaneous pregnancies (GI P = .001; (VI) P = .039) and is almost statistically significant in comparison to the IVF (P = .051). Conclusions: Placental perfusion in pregnancies obtained following oocyte donation is deficient in comparison to spontaneous pregnancies.