Cystic fibrosis and sleep

Sleep disturbances are frequently observed in cystic fibrosis (CF). The resultant sleep fragmentation, short sleep duration, and gas-exchange abnormalities are postulated to contribute to the neurocognitive, cardiovascular, and metabolic abnormalities associated with CF. There are no outcomes data t...

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Bibliographic Details
Published inClinics in chest medicine Vol. 35; no. 3; p. 495
Main Author Katz, Eliot S
Format Journal Article
LanguageEnglish
Published United States 01.09.2014
Subjects
Cystic Fibrosis - physiopathology
Cystic Fibrosis - therapy
Humans
Hypercapnia - physiopathology
Hypoxia - physiopathology
Noninvasive Ventilation
Oxygen Inhalation Therapy
Sleep - physiology
Sleep Apnea, Obstructive - physiopathology
Sleep Wake Disorders - physiopathology
Noninvasive ventilation
Hypoventilation
Hypoxemia
Respiratory insufficiency
Sleep-disordered breathing
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Summary:Sleep disturbances are frequently observed in cystic fibrosis (CF). The resultant sleep fragmentation, short sleep duration, and gas-exchange abnormalities are postulated to contribute to the neurocognitive, cardiovascular, and metabolic abnormalities associated with CF. There are no outcomes data to establish the optimal procedure for screening and treating CF patients for sleep-related respiratory abnormalities. Therapy with supplemental oxygen and bilevel ventilation are widely considered to be effective in the short term, but there are few evidence-based data to support long-term improvements in morbidity and mortality.
ISSN:1557-8216
DOI:10.1016/j.ccm.2014.06.005