Introduction to autoinflammatory syndromes and diseases

Autoinflammatory syndromes and diseases are a group of disorders of innate immunity. This group has grown rapidly in recent years as a result of research advancements in molecular biology and genetics. These diseases often present with skin manifestations and the dermatologist may not recognize the...

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Bibliographic Details
Published inDermatologic clinics Vol. 31; no. 3; p. 363
Main Authors Abramovits, William, Oquendo, Marcial
Format Journal Article
LanguageEnglish
Published United States 01.07.2013
Subjects
Anti-Inflammatory Agents - therapeutic use
Antibodies, Monoclonal - therapeutic use
Autoimmune Diseases - diagnosis
Autoimmune Diseases - drug therapy
Autoimmune Diseases - immunology
Autoimmunity - immunology
Biological Factors - therapeutic use
Diagnosis, Differential
Female
Hereditary Autoinflammatory Diseases - diagnosis
Hereditary Autoinflammatory Diseases - drug therapy
Hereditary Autoinflammatory Diseases - immunology
Humans
Immunity, Innate - immunology
Inflammation - immunology
Interleukin-1 - antagonists & inhibitors
Male
Skin Diseases - diagnosis
Skin Diseases - drug therapy
Skin Diseases - immunology
Syndrome
Familial Mediterranean fever
Inflammasome
Autoinflammation
Interleukins
Recurrent fever
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Summary:Autoinflammatory syndromes and diseases are a group of disorders of innate immunity. This group has grown rapidly in recent years as a result of research advancements in molecular biology and genetics. These diseases often present with skin manifestations and the dermatologist may not recognize the constellation of symptoms and medical history as a systemic inflammatory disease. Dermatologists would benefit from a deeper understanding of these diseases and the new treatments available for them.
ISSN:1558-0520
DOI:10.1016/j.det.2013.04.010