Diagnosing acute HIV infection: The performance of quantitative HIV-1 RNA testing (viral load) in the 2014 laboratory testing algorithm

Highlights • In HIV diagnosis, discordant Combo and Multispot should be resolved by an RNA test. • We found that viral loads worked comparably to the standard assay in this setting. • The viral loads detected in acute HIV infection participants were very high.

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Bibliographic Details
Published inJournal of clinical virology Vol. 93; pp. 85 - 86
Main Authors Wu, Hsiu, Cohen, Stephanie E, Westheimer, Emily, Gay, Cynthia L, Hall, Laura, Rose, Charles, Hightow-Weidman, Lisa B, Gose, Severin, Fu, Jie, Peters, Philip J
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.08.2017
Subjects
Acute HIV infection
Algorithms
Allergy and Immunology
Fourth-generation immunoassay
HIV diagnosis
HIV Infections - blood
HIV Infections - diagnosis
HIV testing
HIV-1 - genetics
Humans
Infectious Disease
Molecular Diagnostic Techniques
Nucleic Acid Amplification Techniques
Quantitative HIV-1 viral load
RNA, Viral - blood
RNA, Viral - genetics
United States
Viral Load
HIV testing
Fourth-generation immunoassay
HIV diagnosis
Quantitative HIV-1 viral load
Acute HIV infection
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Summary:Highlights • In HIV diagnosis, discordant Combo and Multispot should be resolved by an RNA test. • We found that viral loads worked comparably to the standard assay in this setting. • The viral loads detected in acute HIV infection participants were very high.
Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2017.02.005