A model for intra-familial distribution of an infectious disease (Chagas' disease)

A probabilistic model for intra-familial distribution of infectious disease is proposed and applied to the prevalence of positive serology for Trypanosoma cruzi infection in a Northeastern Brazilian sample. This double binomial with one tail excess model fits satisfactorily to the data and its inter...

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Bibliographic Details
Published inMemórias do Instituto Oswaldo Cruz Vol. 88; no. 2; pp. 231 - 233
Main Authors Feitosa, M F, Krieger, H
Format Journal Article
LanguageEnglish
Portuguese
Published Brazil Instituto Oswaldo Cruz, Ministério da Saúde 01.06.1993
Fundação Oswaldo Cruz (FIOCRUZ)
Subjects
Binomial Distribution
Brazil - epidemiology
Chagas Disease - epidemiology
Chagas' disease
double binomial
Family Health
Humans
infectious disease
intra-familial distribution
PARASITOLOGY
Probability
TROPICAL MEDICINE
Brazil
double binomial
Chagas' disease
intra-familial distribution
infectious disease
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Summary:A probabilistic model for intra-familial distribution of infectious disease is proposed and applied to the prevalence of positive serology for Trypanosoma cruzi infection in a Northeastern Brazilian sample. This double binomial with one tail excess model fits satisfactorily to the data and its interpretation says that around 51% of these 982 families are free of infection risk; among those that are at risk, 3% have a high risk (0.66), probably due to high domestic infestation of the vector bug; while 97% show a small risk (0.11), probably due to accidental, non-domestic transmission.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0074-0276
1678-8060
1678-8060
0074-0276
DOI:10.1590/S0074-02761993000200009