ART Initiation for Infants Diagnosed With HIV Through Point of Care and Conventional Polymerase Chain Reaction Testing in Kenya: A Case Series

We sought to understand the sequence of testing and treatment among nine infants offered both conventional and point-of-care testing and diagnosed as HIV-positive by 6 months of age in Kenya. One infant received per protocol testing and treatment. Patient-level (late presentation and disengagement),...

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Bibliographic Details
Published inThe Pediatric infectious disease journal Vol. 40; no. 4; p. e151
Main Authors Wexler, Catherine, Maloba, May, Goggin, Kathy, Kale, Shadrack Babu, Maosa, Nicodemus, Muchoki, Elizabeth, Brown, Melinda, Gautney, Brad, Finocchario-Kessler, Sarah
Format Journal Article
LanguageEnglish
Published United States 01.04.2021
Subjects
Antiretroviral Therapy, Highly Active - methods
Early Diagnosis
Female
HIV - drug effects
HIV - genetics
HIV Infections - diagnosis
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV Infections - virology
Humans
Infant
Infant, Newborn
Kenya
Male
Pilot Projects
Point-of-Care Testing - statistics & numerical data
Polymerase Chain Reaction - methods
Polymerase Chain Reaction - statistics & numerical data
Kenya
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Summary:We sought to understand the sequence of testing and treatment among nine infants offered both conventional and point-of-care testing and diagnosed as HIV-positive by 6 months of age in Kenya. One infant received per protocol testing and treatment. Patient-level (late presentation and disengagement), provider-level (reluctance and error/oversight) and system-level (stock outs, errors) challenges delayed diagnosis and treatment. Early point-of-care testing can streamline testing; however, challenges mitigate benefits.
ISSN:1532-0987
DOI:10.1097/INF.0000000000003032