Amenorrhea, ptosis and high insulin requirement in a young girl

Abstract Lipodystrophy is an uncommon condition leading to excessive insulin requirement and menstrual abnormalities in young girls with diabetes. Neurological symptoms are uncommon in patients of generalized or partial lipodystrophy. We recently encountered a young girl, who presented with high ins...

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Bibliographic Details
Published inDiabetes & metabolic syndrome clinical research & reviews Vol. 10; no. 1; pp. S151 - S153
Main Authors Hari Kumar, K.V.S, Kumar, Sandeep
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.01.2016
Subjects
Adolescent
Amenorrhea - complications
Amenorrhea - pathology
Berardinelli-Seip syndrome
Blepharoptosis - complications
Blepharoptosis - pathology
Diabetes
Diabetes Mellitus - drug therapy
Diabetes Mellitus - pathology
Endocrinology & Metabolism
Female
Humans
Insulin - administration & dosage
Insulin resistance
Lipodystrophy
Lipodystrophy, Congenital Generalized - diagnosis
Puberty
Puberty
Lipodystrophy
Insulin resistance
Diabetes
Berardinelli-Seip syndrome
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Summary:Abstract Lipodystrophy is an uncommon condition leading to excessive insulin requirement and menstrual abnormalities in young girls with diabetes. Neurological symptoms are uncommon in patients of generalized or partial lipodystrophy. We recently encountered a young girl, who presented with high insulin requirement, amenorrhea and neurological symptoms. Detailed evaluation led to the diagnosis of congenital lipodystrophy and we describe the same in this report. We also highlight the atypical features of the congenital lipodystrophy and the reasons for the excessive insulin requirement in patients with diabetes mellitus.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:1871-4021
1878-0334
DOI:10.1016/j.dsx.2015.09.023