Coagulation and immunity: Caught in the fibrin web

In this issue of Immunity, Vega-Pérez et al. (2021) reveal the formation of a dynamic multicellular aggregate within a fibrin scaffold consisting of large peritoneal macrophages, B1 cells, neutrophils, and monocytes during antibacterial immunity in the peritoneum. Anticoagulants targeting thrombin o...

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Published inImmunity (Cambridge, Mass.) Vol. 54; no. 11; pp. 2439 - 2441
Main Authors Sozmen, Elif G., Akassoglou, Katerina
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 09.11.2021
Subjects
Animals
Blood Coagulation
Escherichia coli
Fibrin
Mice
Mice, Inbred C57BL
Monocytes
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Abstract In this issue of Immunity, Vega-Pérez et al. (2021) reveal the formation of a dynamic multicellular aggregate within a fibrin scaffold consisting of large peritoneal macrophages, B1 cells, neutrophils, and monocytes during antibacterial immunity in the peritoneum. Anticoagulants targeting thrombin or peritoneal macrophage depletion by clodronate impaired efficient control of E. coli infection. In this issue of Immunity, Vega-Pérez et al. (2021) reveal the formation of a dynamic multicellular aggregate within a fibrin scaffold consisting of large peritoneal macrophages, B1 cells, neutrophils, and monocytes during antibacterial immunity in the peritoneum. Anticoagulants targeting thrombin or peritoneal macrophage depletion by clodronate impaired efficient control of E. coli infection.
AbstractList In this issue of Immunity, Vega-Pérez et al. (2021) reveal the formation of a dynamic multicellular aggregate within a fibrin scaffold consisting of large peritoneal macrophages, B1 cells, neutrophils, and monocytes during antibacterial immunity in the peritoneum. Anticoagulants targeting thrombin or peritoneal macrophage depletion by clodronate impaired efficient control of E. coli infection. In this issue of Immunity, Vega-Pérez et al. (2021) reveal the formation of a dynamic multicellular aggregate within a fibrin scaffold consisting of large peritoneal macrophages, B1 cells, neutrophils, and monocytes during antibacterial immunity in the peritoneum. Anticoagulants targeting thrombin or peritoneal macrophage depletion by clodronate impaired efficient control of E. coli infection.
In this issue of Immunity, Vega-Pérez et al. (2021) reveal the formation of a dynamic multicellular aggregate within a fibrin scaffold consisting of large peritoneal macrophages, B1 cells, neutrophils, and monocytes during antibacterial immunity in the peritoneum. Anticoagulants targeting thrombin or peritoneal macrophage depletion by clodronate impaired efficient control of E. coli infection.
Author Akassoglou, Katerina
Sozmen, Elif G.
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10.1084/jem.20182024
10.1016/S0140-6736(63)92808-3
10.1016/S0092-8674(00)81390-2
10.1038/35025229
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References Davalos, Akassoglou (bib3) 2012; 34
Luyendyk, Schoenecker, Flick (bib6) 2019; 133
Nelson (bib7) 1963; 2
Petersen, Ryu, Akassoglou (bib8) 2018; 19
Bugge, Kombrinck, Flick, Daugherty, Danton, Degen (bib1) 1996; 87
Vega-Pérez, Villarrubia, Godio, Gutiérrez-González, Feo-Lucas, Ferriz, Martínez-Puente, Alcaín, Mora, Sabio (bib9) 2021; 54
Esmon (bib5) 2003; 1
Davalos, Ryu, Merlini, Baeten, Le Moan, Petersen, Deerinck, Smirnoff, Bedard, Hakozaki (bib4) 2012; 3
Zhang, Czepielewski, Jarjour, Erlich, Esaulova, Saunders, Grover, Cleuren, Broze, Edelson (bib10) 2019; 216
Coughlin (bib2) 2000; 407
34717795 - Immunity. 2021 Nov 9;54(11):2578-2594.e5
Bugge (10.1016/j.immuni.2021.10.016_bib1) 1996; 87
Davalos (10.1016/j.immuni.2021.10.016_bib3) 2012; 34
Vega-Pérez (10.1016/j.immuni.2021.10.016_bib9) 2021; 54
Zhang (10.1016/j.immuni.2021.10.016_bib10) 2019; 216
Coughlin (10.1016/j.immuni.2021.10.016_bib2) 2000; 407
Nelson (10.1016/j.immuni.2021.10.016_bib7) 1963; 2
Esmon (10.1016/j.immuni.2021.10.016_bib5) 2003; 1
Luyendyk (10.1016/j.immuni.2021.10.016_bib6) 2019; 133
Petersen (10.1016/j.immuni.2021.10.016_bib8) 2018; 19
Davalos (10.1016/j.immuni.2021.10.016_bib4) 2012; 3
References_xml – volume: 54
  start-page: 2578
  year: 2021
  end-page: 2594
  ident: bib9
  article-title: Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity
  publication-title: Immunity
  contributor:
    fullname: Sabio
– volume: 216
  start-page: 1291
  year: 2019
  end-page: 1300
  ident: bib10
  article-title: Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity
  publication-title: J. Exp. Med.
  contributor:
    fullname: Edelson
– volume: 87
  start-page: 709
  year: 1996
  end-page: 719
  ident: bib1
  article-title: Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency
  publication-title: Cell
  contributor:
    fullname: Degen
– volume: 19
  start-page: 283
  year: 2018
  end-page: 301
  ident: bib8
  article-title: Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics
  publication-title: Nat. Rev. Neurosci.
  contributor:
    fullname: Akassoglou
– volume: 407
  start-page: 258
  year: 2000
  end-page: 264
  ident: bib2
  article-title: Thrombin signalling and protease-activated receptors
  publication-title: Nature
  contributor:
    fullname: Coughlin
– volume: 34
  start-page: 43
  year: 2012
  end-page: 62
  ident: bib3
  article-title: Fibrinogen as a key regulator of inflammation in disease
  publication-title: Semin. Immunopathol.
  contributor:
    fullname: Akassoglou
– volume: 3
  start-page: 1227
  year: 2012
  ident: bib4
  article-title: Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
  publication-title: Nat. Commun.
  contributor:
    fullname: Hakozaki
– volume: 1
  start-page: 1343
  year: 2003
  end-page: 1348
  ident: bib5
  article-title: Inflammation and thrombosis
  publication-title: J. Thromb. Haemost.
  contributor:
    fullname: Esmon
– volume: 2
  start-page: 175
  year: 1963
  end-page: 176
  ident: bib7
  article-title: Reaction to antigens in vivo of the peritoneal macrophages of guinea-pigs with delayed type hypersensitivity. Effects of anticoagulants and other drugs
  publication-title: Lancet
  contributor:
    fullname: Nelson
– volume: 133
  start-page: 511
  year: 2019
  end-page: 520
  ident: bib6
  article-title: The multifaceted role of fibrinogen in tissue injury and inflammation
  publication-title: Blood
  contributor:
    fullname: Flick
– volume: 54
  start-page: 2578
  year: 2021
  ident: 10.1016/j.immuni.2021.10.016_bib9
  article-title: Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity
  publication-title: Immunity
  doi: 10.1016/j.immuni.2021.10.007
  contributor:
    fullname: Vega-Pérez
– volume: 133
  start-page: 511
  year: 2019
  ident: 10.1016/j.immuni.2021.10.016_bib6
  article-title: The multifaceted role of fibrinogen in tissue injury and inflammation
  publication-title: Blood
  doi: 10.1182/blood-2018-07-818211
  contributor:
    fullname: Luyendyk
– volume: 3
  start-page: 1227
  year: 2012
  ident: 10.1016/j.immuni.2021.10.016_bib4
  article-title: Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
  publication-title: Nat. Commun.
  doi: 10.1038/ncomms2230
  contributor:
    fullname: Davalos
– volume: 1
  start-page: 1343
  year: 2003
  ident: 10.1016/j.immuni.2021.10.016_bib5
  article-title: Inflammation and thrombosis
  publication-title: J. Thromb. Haemost.
  doi: 10.1046/j.1538-7836.2003.00261.x
  contributor:
    fullname: Esmon
– volume: 216
  start-page: 1291
  year: 2019
  ident: 10.1016/j.immuni.2021.10.016_bib10
  article-title: Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity
  publication-title: J. Exp. Med.
  doi: 10.1084/jem.20182024
  contributor:
    fullname: Zhang
– volume: 2
  start-page: 175
  year: 1963
  ident: 10.1016/j.immuni.2021.10.016_bib7
  article-title: Reaction to antigens in vivo of the peritoneal macrophages of guinea-pigs with delayed type hypersensitivity. Effects of anticoagulants and other drugs
  publication-title: Lancet
  doi: 10.1016/S0140-6736(63)92808-3
  contributor:
    fullname: Nelson
– volume: 87
  start-page: 709
  year: 1996
  ident: 10.1016/j.immuni.2021.10.016_bib1
  article-title: Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)81390-2
  contributor:
    fullname: Bugge
– volume: 407
  start-page: 258
  year: 2000
  ident: 10.1016/j.immuni.2021.10.016_bib2
  article-title: Thrombin signalling and protease-activated receptors
  publication-title: Nature
  doi: 10.1038/35025229
  contributor:
    fullname: Coughlin
– volume: 34
  start-page: 43
  year: 2012
  ident: 10.1016/j.immuni.2021.10.016_bib3
  article-title: Fibrinogen as a key regulator of inflammation in disease
  publication-title: Semin. Immunopathol.
  doi: 10.1007/s00281-011-0290-8
  contributor:
    fullname: Davalos
– volume: 19
  start-page: 283
  year: 2018
  ident: 10.1016/j.immuni.2021.10.016_bib8
  article-title: Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics
  publication-title: Nat. Rev. Neurosci.
  doi: 10.1038/nrn.2018.13
  contributor:
    fullname: Petersen
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SubjectTerms Animals
Blood Coagulation
Escherichia coli
Fibrin
Mice
Mice, Inbred C57BL
Monocytes
Title Coagulation and immunity: Caught in the fibrin web
URI https://dx.doi.org/10.1016/j.immuni.2021.10.016
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