Immunologic Effects of the Microbiota in Organ Transplantation

The microbiota is a community of microbes that colonizes body surfaces. It has many effects that influence immune activation and regulation. The success of organ transplantation is limited by rejection of grafts by the immune system so it is important to understand how immunologic responses are cont...

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Bibliographic Details
Published inClinics in laboratory medicine Vol. 39; no. 1; p. 185
Main Authors Rey, Kevin, Choy, Jonathan C
Format Journal Article
LanguageEnglish
Published United States 01.03.2019
Subjects
Microbiota
Immune regulation
Transplantation
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Summary:The microbiota is a community of microbes that colonizes body surfaces. It has many effects that influence immune activation and regulation. The success of organ transplantation is limited by rejection of grafts by the immune system so it is important to understand how immunologic responses are controlled in this setting. This review discusses the immunologic effects of the microbiota and how this microbial community may affect organ transplant rejection.
ISSN:1557-9832
DOI:10.1016/j.cll.2018.10.010