Retroperitoneal fibrosis

Retroperitoneal fibrosis (RPF) is a condition characterized by the presence of inflammation and fibrosis in the retroperitoneal space, for which no standard diagnostic criteria exist. Historically, treatment has focused on relieving the obstruction with percutaneous or cystoscopic assisted placement...

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Bibliographic Details
Published inRheumatic diseases clinics of North America Vol. 39; no. 2; p. 365
Main Authors Scheel, Jr, Paul J, Feeley, Nancy
Format Journal Article
LanguageEnglish
Published United States 01.05.2013
Subjects
Aortic Diseases - epidemiology
Aortic Diseases - pathology
Comorbidity
Disease Management
Humans
Immunosuppressive Agents - therapeutic use
Retroperitoneal Fibrosis - epidemiology
Retroperitoneal Fibrosis - pathology
Retroperitoneal Fibrosis - physiopathology
Retroperitoneal Fibrosis - therapy
Stents
Ureter - surgery
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Summary:Retroperitoneal fibrosis (RPF) is a condition characterized by the presence of inflammation and fibrosis in the retroperitoneal space, for which no standard diagnostic criteria exist. Historically, treatment has focused on relieving the obstruction with percutaneous or cystoscopic assisted placement of ureteral stents followed by more definitive resolution of ureteric obstruction with open or laparoscopic ureterolysis. However, over the past several years management has shifted from primarily a surgical approach to an immunosuppressive-based therapy aimed at modulation of the immune system. This review focuses on the recent advances in the classification, epidemiology, pathophysiology, pathology, imaging, and treatment of RPF.
ISSN:1558-3163
DOI:10.1016/j.rdc.2013.02.004