Modifiable Risk Factors in Necrotizing Enterocolitis

Multicenter groups have reported reductions in the incidence of necrotizing enterocolitis (NEC) among preterm infants over the past 2 decades. These large-scale prevalence studies have coincided with reports from multicenter consortia and single centers of modifications in practice using quality-imp...

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Bibliographic Details
Published inClinics in perinatology Vol. 46; no. 1; p. 129
Main Author Cotten, C Michael
Format Journal Article
LanguageEnglish
Published United States 01.03.2019
Subjects
Quality improvement
Antibiotics
Human milk
Necrotizing enterocolitis
Transfusions
Breastfeeding
Antacids
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Summary:Multicenter groups have reported reductions in the incidence of necrotizing enterocolitis (NEC) among preterm infants over the past 2 decades. These large-scale prevalence studies have coincided with reports from multicenter consortia and single centers of modifications in practice using quality-improvement techniques aimed at either reducing NEC risk specifically or reducing risk of mortality and multiple morbidities associated with extreme prematurity. The modifications in practice have been based on mechanistic studies, epidemiologic association data, and clinical trials. Recent reports from centers modifying practice to reduce NEC are reviewed and select modified/modifiable practices discussed.
ISSN:1557-9840
DOI:10.1016/j.clp.2018.10.007