Physiology of sleep and breathing before and after lung transplantation

During the past 20 years, lung transplantation (LTX) has evolved and it is now accepted as a mainstream modality for care of patients with severe life-threatening respiratory diseases that are refractory to maximal conventional therapies. Improvements in surgical techniques and in antirejection medi...

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Bibliographic Details
Published inClinics in chest medicine Vol. 35; no. 3; p. 513
Main Authors Pierucci, Paola, Malouf, Monique
Format Journal Article
LanguageEnglish
Published United States 01.09.2014
Subjects
Cardiovascular Diseases - epidemiology
Comorbidity
Cystic Fibrosis - physiopathology
Gastroesophageal Reflux - epidemiology
Gastroesophageal Reflux - physiopathology
Humans
Lung Transplantation - methods
Respiratory Insufficiency - physiopathology
Respiratory Insufficiency - surgery
Sleep - physiology
Sleep Apnea Syndromes - physiopathology
Waiting Lists
Weight Gain - physiology
CSA
SDB
Sleep disorders
OSA
Lung transplant
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Summary:During the past 20 years, lung transplantation (LTX) has evolved and it is now accepted as a mainstream modality for care of patients with severe life-threatening respiratory diseases that are refractory to maximal conventional therapies. Improvements in surgical techniques and in antirejection medications have resulted in prolonged survival in these patients. Several studies have explored quality of life after LTX and its improvement has been noted especially in the early period between 3 and 6 months. This article discusses the salient features of the physiology of breathing and sleep disturbances before and after LTX and its alterations during sleep.
ISSN:1557-8216
DOI:10.1016/j.ccm.2014.06.007