Efficacy of dupilumab as an alternative to corticosteroids in the treatment of exacerbations of allergic bronchopulmonary aspergillosis

The pathogenesis of allergic bronchopulmonary aspergillosis involves not only eosinophils but also plasma cells that produce immunoglobulin E. Dupilumab may be an effective alternative to corticosteroids because it inhibits T cell to plasma cell differentiation by blocking IL4.

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Bibliographic Details
Published inRespirology case reports Vol. 12; no. 4; pp. e01354 - n/a
Main Authors Hamakawa, Masamitsu, Ishida, Tadashi
Format Journal Article
LanguageEnglish
Published United States John Wiley & Sons, Inc 01.04.2024
Wiley
Subjects
ABPA
allergic bronchopulmonary aspergillosis
Aspergillosis
asthma
dupilumab
Steroids
asthma
allergic bronchopulmonary aspergillosis
ABPA
dupilumab
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Summary:The pathogenesis of allergic bronchopulmonary aspergillosis involves not only eosinophils but also plasma cells that produce immunoglobulin E. Dupilumab may be an effective alternative to corticosteroids because it inhibits T cell to plasma cell differentiation by blocking IL4.
ISSN:2051-3380
2051-3380
DOI:10.1002/rcr2.1354