A Brief Report on Outcomes of Stereotactic Ablative Radiotherapy for a Second Primary Lung Cancer: Evidence in Support of Routine CT Surveillance

• Published in: Journal of thoracic oncology Vol. 9; no. 8; pp. 1222 - 1225
• Main Authors: Griffioen, Gwendolyn H.M.J., Lagerwaard, Frank J., Haasbeek, Cornelis J.A., Slotman, Ben J., Senan, Suresh
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2014
• Subjects: Aged; Aged, 80 and over; Disease-Free Survival; Female; Hemoptysis - etiology; Humans; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - surgery; Male; Middle Aged; Neoplasms, Second Primary - diagnostic imaging; Neoplasms, Second Primary - surgery; Pneumonectomy; Population Surveillance; Radiation Pneumonitis - etiology; Radiosurgery - adverse effects; Survival Rate; Tomography, X-Ray Computed
• ISSN: 1556-0864; 1556-1380
• DOI: 10.1097/JTO.0000000000000218

New guidelines recommend the use of CT surveillance after a curative treatment for lung cancer as survivors have a 3–6% risk per person year of developing a second primary lung cancer. Our analysis of 107 patients with second primary lung cancer treated by stereotactic ablative radiotherapy showed a comparable 3 years overall survival (60%) and local control rate (89%) as for an initial lung cancer. Toxicity was uncommon, despite the fact that 73% of patients had undergone a prior (bi)lobectomy. Our findings indicate that CT surveillance is also appropriate in patients who may be unfit, or unwilling, to undergo surgery.