Use of Buprenorphine in treatment of refractory depression—A review of current literature

• Published in: Asian journal of psychiatry Vol. 26; pp. 94 - 98
• Main Authors: Stanciu, Cornel N, Glass, Oliver M, Penders, Thomas M
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2017
• Subjects: Analgesics, Opioid - therapeutic use; Antidepressive Agents - therapeutic use; Buprenorphine; Buprenorphine - therapeutic use; Depressive Disorder, Treatment-Resistant - drug therapy; Humans; Internal Medicine; Psychiatry; Treatment Outcome; Treatment resistant depression; Buprenorphine; Treatment resistant depression

Highlights • For treatment resistant depression, augmentation strategies may improve outcome in some, leaving many with disabling and distressing residual symptoms. • Based on the endogenous opioid system literature, Buprenorphine displays a rapid acting antidepressant effect at low doses. • Bupreno...