Pharmacotherapy of pediatric attention-deficit/hyperactivity disorder

• Published in: Child and adolescent psychiatric clinics of North America Vol. 21; no. 4; p. 941
• Main Authors: Vaughan, Brigette, Kratochvil, Christopher J
• Format: Journal Article
• Language: English
• Published: United States 01.10.2012
• Subjects: Adolescent; Adrenergic Uptake Inhibitors - administration & dosage; Adrenergic Uptake Inhibitors - adverse effects; Amphetamines - administration & dosage; Amphetamines - adverse effects; Attention Deficit Disorder with Hyperactivity - drug therapy; Central Nervous System Stimulants - administration & dosage; Central Nervous System Stimulants - adverse effects; Child; Child, Preschool; Clinical Trials as Topic; Humans; Male
• ISSN: 1558-0490
• DOI: 10.1016/j.chc.2012.07.005

This article describes the practical use of available attention-deficit/hyperactivity disorder (ADHD) pharmacotherapies, their formulations and durations of action, and the extent of Food and Drug Administration approvals. It provides data on short-term and long-term safety of these medications, their use in ADHD with comorbid conditions, and strategies for formulating individualized, effective, and well-tolerated pharmacotherapy treatment plans. A clinical vignette focusing on a male child with ADHD is presented. Summaries are presented of ADHD pharmacotherapies and Food and Drug Administration approval status, atomoxetine and stimulant comparator trials, adverse effects and ADHD pharmacotherapy, and delivery system and duration of effect.