Effects of heavy-atom substituents on matrices used for matrix-assisted laser desorption-ionization mass spectrometry
The data reported show that heavy-atom substitution on matrices that are used for matrix-assisted laser desorption-ionization mass spectrometry enhance [M + H] + ion yields of both Leu-enkephalin and vitamin B 12. Heavy-atom substitution alters the excited state relaxation dynamics of the matrices a...
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Published in | Journal of the American Society for Mass Spectrometry Vol. 5; no. 9; pp. 800 - 806 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.09.1994
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Online Access | Get full text |
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Summary: | The data reported show that heavy-atom substitution on matrices that are used for matrix-assisted laser desorption-ionization mass spectrometry enhance [M + H]
+ ion yields of both Leu-enkephalin and vitamin B
12. Heavy-atom substitution alters the excited state relaxation dynamics of the matrices as indicated by measured decreases in the measured luminescence (fluorescence and/or phosphorescence) observed for heavy atoms that contain matrices relative to the nonheavy-atom-substituted matrices. The results presented are consistent with the direct involvement of an electronically excited state of the matrix in the formation of analyte [M + H]
+ ions. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1044-0305 1879-1123 |
DOI: | 10.1016/1044-0305(94)87002-0 |