Validation of a Novel System for Co-Registration of Coronary Angiographic and Intravascular Ultrasound Imaging
Intravascular ultrasound (IVUS) is a useful adjunct to guide percutaneous coronary intervention (PCI). Correlating IVUS images with angiographic findings can be challenging. We evaluated the utility of a novel co-registration system for IVUS and coronary angiography. A 3-D virtual catheter trajector...
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Published in | Cardiovascular revascularization medicine Vol. 20; no. 9; pp. 775 - 781 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.09.2019
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Subjects | |
Online Access | Get full text |
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Summary: | Intravascular ultrasound (IVUS) is a useful adjunct to guide percutaneous coronary intervention (PCI). Correlating IVUS images with angiographic findings can be challenging. We evaluated the utility of a novel co-registration system for IVUS and coronary angiography.
A 3-D virtual catheter trajectory was constructed from separate angiographic imaging runs using bespoke software. Intravascular ultrasound images were obtained using a commercially available mechanical rotational transducer with motorized pullback. Co-registration of ultrasound and angiographic images was then performed retrospectively based on the length of pullback, the 3-D trajectory and the start position of the catheter. Validation was performed in a spherical phantom model and in vivo in the coronary circulation of patients undergoing coronary angiography and intravascular imaging for clinical purposes. 111 paired angiographic and IVUS runs were performed in 3 phantom models. The differences between the reference length and the length measured on the 3D reconstructed path was −0.01 ± 0.40 mm. Intra-observer variability was 0.4%.
We enrolled 25 patients in 3 European hospitals and performed 35 co-registration attempts with an 86% success rate. 71 landmarks were selected by the first operator, 68 by the second. Differences between angiographic and IVUS landmarks were −0.22 ± 0.72 mm and 0.05 ± 1.01 mm, respectively. Inter-observer variability was 0.23 ± 0.63 mm.
We present a novel method for the co-registration of IVUS and coronary angiographic images. This system performed well in a phantom model and using images obtained from the human coronary circulation.
Innovation, intravascular ultrasound, other technique
•Correlating IVUS images with angiographic findings can be challenging.•We evaluated the utility of a novel co-registration system for IVUS and coronary angiography.•A 3-D virtual catheter trajectory was constructed from separate angiographic imaging runs using bespoke software.•IVUS images were co-registered to angiographic images based on the length of pullback, the 3-D trajectory and the start position of the catheter.•Validation was performed in a spherical phantom model and in vivo in patients undergoing clinically indicated coronary angiography and IVUS. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 |
ISSN: | 1553-8389 1878-0938 |
DOI: | 10.1016/j.carrev.2018.10.024 |