Assessment of Right Ventricular Mechanics in Patients with Mitral Stenosis by Two-Dimensional Deformation Imaging

• Published in: Echocardiography (Mount Kisco, N.Y.) Vol. 29; no. 8; pp. 956 - 961
• Main Authors: Tanboga, Ibrahim Halil, Kurt, Mustafa, Bilen, Emine, Aksakal, Enbiya, Kaya, Ahmet, Isik, Turgay, Ekinci, Mehmet, Karakoyun, Süleyman, Sevimli, Serdar
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01.09.2012
• Subjects: Adult; Echocardiography, Doppler - methods; Elastic Modulus; Elasticity Imaging Techniques - methods; Female; Heart Ventricles - diagnostic imaging; Heart Ventricles - physiopathology; Humans; Male; mitral stenosis; Mitral Valve Stenosis - complications; Mitral Valve Stenosis - diagnostic imaging; Mitral Valve Stenosis - physiopathology; Reproducibility of Results; right ventricle; Sensitivity and Specificity; Ventricular Dysfunction, Right - diagnostic imaging; Ventricular Dysfunction, Right - etiology; Ventricular Dysfunction, Right - physiopathology
• ISSN: 0742-2822; 1540-8175; 1540-8175
• DOI: 10.1111/j.1540-8175.2012.01738.x

Background: It is well known that right ventricular (RV) dysfunction occurs early before clinical systemic congestion in patients with mitral stenosis (MS). Therefore, we aimed to evaluate the role of two‐dimensional (2D) strain imaging in the assessment of subclinical RV dysfunction. Methods: Fifty‐nine patients with isolated MS (mild and moderate) and 31 healthy control subjects constituted the study population. RV peak longitudinal strain (RV‐LS) and strain rate (RV‐LSr) measurements were obtained from apical four‐chamber view. Results: There were no significant differences in left ventricular ejection fraction (LV‐EF) and RV fractional area change between control and MS groups. RV strain (23.5 ± 7.2 vs. 18.63 ± 6.3, P = 0.001) and RV strain rate (1.72 ± 0.54 vs. 1.37 ± 0.66, P = 0.01) measurements were significantly lower in patients with MS than the control group. However, RV strain and strain rate measurements were comparable between MS subgroups. Correlation analysis revealed that there was poor correlation between RV‐LS/LSr and mean‐maximum gradients and echoscore but moderate correlation between RV‐LS and RV‐Sr in systolic pulmonary artery pressure and planimetric mitral valve area. Conclusion: We demonstrated that patients with MS had lower RV functions using 2D strain imaging and this is independent from severity of MS. In the detection of subclinical RV dysfunction in patients with MS, 2D strain imaging appears to be useful. (Echocardiography, 2012;00:1–6)