A Practical and Highly Active Ruthenium-Based Catalyst that Effects the Cross Metathesis of Acrylonitrile

• Published in: Angewandte Chemie International Edition Vol. 41; no. 21; pp. 4035 - 4037
• Main Authors: Love, Jennifer A., Morgan, John P., Trnka, Tina M., Grubbs, Robert H.
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 04.11.2002; WILEY‐VCH Verlag; Wiley
• Subjects: Acrylonitrile - chemical synthesis; Acrylonitrile - chemistry; Catalysis; Chemistry; Chemistry, Multidisciplinary; Heterocyclic Compounds - chemistry; homogeneous catalysis; Kinetics; metathesis; Molecular Structure; N ligands; Physical Sciences; Pyridines - chemical synthesis; Pyridines - chemistry; ruthenium; Ruthenium Compounds - chemistry; Science & Technology; ALKENES; COMPLEX; LIGANDS; MECHANISM; OLEFIN METATHESIS; EFFICIENT; VINYLPHOSPHONATE
• ISSN: 1433-7851; 1521-3773
• DOI: 10.1002/1521-3773(20021104)41:21<4035::AID-ANIE4035>3.0.CO;2-I

The highest initiation rate of any reported ruthenium‐based catalyst was found for the new olefin‐metathesis catalyst [(H2IMes)(3‐Br‐py)2(Cl)2RuCHPh] (1), which was synthesized in one step from commercially available reagents. Complex 1 is highly efficient for the cross metathesis of acrylonitrile, which is generally a poor substrate for metathesis reactions (e.g., see scheme). Mes=2,4,6‐trimethylphenyl.