Recent Advances in Wearable Potentiometric pH Sensors

• Published in: Membranes (Basel) Vol. 12; no. 5; p. 504
• Main Authors: Tang, Yitian, Zhong, Lijie, Wang, Wei, He, Ying, Han, Tingting, Xu, Longbin, Mo, Xiaocheng, Liu, Zhenbang, Ma, Yingming, Bao, Yu, Gan, Shiyu, Niu, Li
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 09.05.2022; MDPI
• Subjects: Acne; Biochemical markers; Biological activity; Biomarkers; Biomonitoring; Chemical sensors; Dermatitis; Electrochemistry; Electrodes; Flexibility; Human mechanics; ion-selective electrode; Ionophores; Medical equipment; Metal oxides; pH effects; pH sensors; Polyanilines; Polymerization; potentiometric sensors; Precision medicine; Review; Saliva; Sensors; Tattoos; Wearable computers; wearable sensors; Wearable technology; ion-selective electrode; potentiometric sensors; pH sensors; wearable sensors
• ISSN: 2077-0375; 2077-0375
• DOI: 10.3390/membranes12050504

Wearable sensors reflect the real-time physiological information and health status of individuals by continuously monitoring biochemical markers in biological fluids, including sweat, tears and saliva, and are a key technology to realize portable personalized medicine. Flexible electrochemical pH sensors can play a significant role in health since the pH level affects most biochemical reactions in the human body. pH indicators can be used for the diagnosis and treatment of diseases as well as the monitoring of biological processes. The performances and applications of wearable pH sensors depend significantly on the properties of the pH-sensitive materials used. At present, existing pH-sensitive materials are mainly based on polyaniline (PANI), hydrogen ionophores (HIs) and metal oxides (MO ). In this review, we will discuss the recent progress in wearable pH sensors based on these sensitive materials. Finally, a viewpoint for state-of-the-art wearable pH sensors and a discussion of their existing challenges are presented.