Feasibility of Right Ventricular Longitudinal Systolic Function Evaluation with Transthoracic Echocardiographic Indices Derived from Tricuspid Annular Motion: A Preliminary Study in Acute Respiratory Distress Syndrome

• Published in: Echocardiography (Mount Kisco, N.Y.) Vol. 29; no. 5; pp. 513 - 521
• Main Authors: Fichet, Jérôme, Moreau, Laure, Genée, Olivier, Legras, Annick, Mercier, Emmanuelle, Garot, Denis, Dequin, Pierre-François, Perrotin, Dominique
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01.05.2012
• Subjects: Adult; Aged; ARDS; echocardiography; Echocardiography - methods; Feasibility Studies; Female; Humans; Male; mechanical ventilation; Middle Aged; monitoring; Pilot Projects; Reproducibility of Results; Respiratory Distress Syndrome, Adult - complications; Respiratory Distress Syndrome, Adult - diagnostic imaging; right ventricle; Sensitivity and Specificity; Stroke Volume; Tricuspid Valve - diagnostic imaging; Ventricular Dysfunction, Right - diagnostic imaging; Ventricular Dysfunction, Right - etiology
• ISSN: 0742-2822; 1540-8175
• DOI: 10.1111/j.1540-8175.2011.01650.x

Introduction: Assessment of right ventricular (RV) function in patients with acute respiratory distress syndrome (ARDS) remains challenging. Transthoracic echocardiographic (TTE) indices based on longitudinal systolic RV function are now considered as a reliable evaluation of RV function. We investigated feasibility of two methods in ARDS patients. Methods: Prospective observational study. TTE was performed after 12–36 hours of mechanical ventilation. Feasibility of tricuspid annular motion (St), tricuspid annular plane systolic excursion (TAPSE) was compared to usual two‐dimensional (2D) study: fractional area change (RVFAC) and ratio of right to left ventricular end‐diastolic area (RVEDA/LVEDA). Results: Fifty patients were investigated, with TTE possible in all but two patients. Feasibility was 62% for RVFAC, 72% for RVEDA/LVEDA, and 96% for TAPSE and St. RV dilatation (RVEDA/LVEDA ≥0.60) was found in 16 patients, including 4 patients with acute cor pulmonale. A longitudinal RV dysfunction (TAPSE < 12 mm or St < 11.5 cm/sec) was suspected in 30% of patients. Relation between both longitudinal indices was modest (r2= 0.36, P < 0.001). TAPSE (but not St) was found poorly related to RVFAC (r2= 0.27, P = 0.03). Both indices were related to LV function (St: r2= 0.27, TAPSE: r2= 0.17, both P < 0.05). Conclusion: Despite a superior feasibility than 2D study, our results suggest that both indices may not bring identical information to echo study. TAPSE may be more adapted to ICU use than St. Both should be further investigated in terms of analysis of RV function and ventricular interdependence. Their relations with LV function may limit their use as sole markers of RV function in this population. (Echocardiography 2012;29:513‐521)