Rotaxa-polymeric-gelation of acrylamides with vinyl-β-cyclodextrin

• Published in: Journal of inclusion phenomena and macrocyclic chemistry Vol. 98; no. 1-2; pp. 43 - 48
• Main Authors: Kobayashi, Yuki, Kojima, Yu, Miki, Ryotaro, Seki, Toshinobu, Egawa, Yuya
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.10.2020; Springer Nature B.V
• Subjects: Acrylamide; Chemistry; Chemistry and Materials Science; Copolymerization; Copolymers; Crosslinking; Crystallography and Scattering Methods; Cyclodextrins; Food Science; Gelation; Hydrogels; Isoprene; Isopropylacrylamide; Organic Chemistry; Original Article; Rotaxanes; Acrylamide; Cyclodextrin; Polyrotaxane; Rotaxa-polymeric-gelation; isopropylacrylamide
• ISSN: 1388-3127; 1573-1111
• DOI: 10.1007/s10847-020-01007-9

Previously, we have reported a single-step preparation method for a topological gel by copolymerizing isoprene and vinyl-modified β-cyclodextrin (V-β-CyD). In the prepared gel, the vinyl part of V-β-CyD consists a part of the copolymer chain, and the β-CyD part includes another copolymer chain, thus V-β-CyD works as a cross-linker. We call the procedure rotaxa-polymeric-gelation (RPG) because polymerization, rotaxane formation, and gelation proceed simultaneously. In this study, we applied acrylamide (AAm) instead of isoprene for RPG, and successfully obtained highly swellable hydrogel. By contrast, a combination of V-β-CyD and N -isopropylacrylamide (NIPAAm) was not suitable for RPG because NIPAAm and cavity of β-CyD were mismatched in size. In addition, we prepared three-component gels. Among of them, gels composed of NIPAAm, isoprene, and V-β-CyD showed thermo-responsiveness by reflecting the character of polyNIPAAm. These results provide an insight for usage of vinyl monomers for RPG strategy.