Neurobiological basis of autism

Autism (autism spectrum disorders) is a complex, strongly genetically influenced, behaviorally defined disorder of the immature brain associated with very uneven intellectual abilities. Among its most salient and potentially treatable neurologic features that this article focuses on are epilepsy, di...

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Bibliographic Details
Published inThe Pediatric clinics of North America Vol. 59; no. 1; p. 45
Main Authors Silver, Wendy G, Rapin, Isabelle
Format Journal Article
LanguageEnglish
Published United States 01.02.2012
Subjects
Adolescent
Brain - physiopathology
Child
Child Development Disorders, Pervasive - complications
Child Development Disorders, Pervasive - diagnosis
Child Development Disorders, Pervasive - genetics
Child Development Disorders, Pervasive - physiopathology
Child, Preschool
Diagnostic Imaging
Epilepsy - complications
Epilepsy - physiopathology
Humans
Infant
Infant, Newborn
Motor Skills Disorders - complications
Motor Skills Disorders - physiopathology
Sensation Disorders - complications
Sensation Disorders - physiopathology
Sleep Wake Disorders - complications
Sleep Wake Disorders - physiopathology
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Summary:Autism (autism spectrum disorders) is a complex, strongly genetically influenced, behaviorally defined disorder of the immature brain associated with very uneven intellectual abilities. Among its most salient and potentially treatable neurologic features that this article focuses on are epilepsy, disorganized sleep patterns, and sensory and motor deficits. Its many causes and wide range of severity means that there is no symptom, no pathology, imaging, electroencephalography, or other biologic feature, and no biologic treatment that is universal or diagnostic of this developmental syndrome.
ISSN:1557-8240
DOI:10.1016/j.pcl.2011.10.010