The use of human acellular dermal matrices in irradiated breast reconstruction

This article examines the effects of radiation on prosthetic breast reconstruction when human dermal allograft is used in the reconstruction. A brief review of radiation terminology and techniques as applied to the breast is given, followed by a review of the effects of radiation on wound healing in...

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Bibliographic Details
Published inClinics in plastic surgery Vol. 39; no. 2; p. 149
Main Author Topol, Bruce M
Format Journal Article
LanguageEnglish
Published United States 01.04.2012
Subjects
Animals
Breast Neoplasms - radiotherapy
Collagen
Female
Humans
Mammaplasty - methods
Radiation Injuries - etiology
Radiation Injuries - surgery
Skin, Artificial
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Summary:This article examines the effects of radiation on prosthetic breast reconstruction when human dermal allograft is used in the reconstruction. A brief review of radiation terminology and techniques as applied to the breast is given, followed by a review of the effects of radiation on wound healing in human tissue. The effects of radiation on prosthetic breast reconstruction before the advent of dermal allografting are reviewed. The addition of dermal allograft in reconstruction has led to a reduced number of complications. An algorithm for surgical treatment of irradiated prosthetic breast reconstructions is presented, with a discussion of the authors technique.
ISSN:1558-0504
DOI:10.1016/j.cps.2012.02.002