PRIdictor: Protein–RNA Interaction predictor

Several computational methods have been developed to predict RNA-binding sites in protein, but its inverse problem (i.e., predicting protein-binding sites in RNA) has received much less attention. Furthermore, most methods that predict RNA-binding sites in protein do not consider interaction partner...

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Bibliographic Details
Published inBioSystems Vol. 139; pp. 17 - 22
Main Authors Tuvshinjargal, Narankhuu, Lee, Wook, Park, Byungkyu, Han, Kyungsook
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 01.01.2016
Subjects
Amino Acids - metabolism
Binding Sites
Computational Biology
Prediction
Protein-binding ribonucleotide
Proteins - metabolism
Ribonucleotides - metabolism
RNA - metabolism
RNA-binding amino acid
Support Vector Machine
Web server
Protein-binding ribonucleotide
RNA-binding amino acid
Support vector machine
Web server
Prediction
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Summary:Several computational methods have been developed to predict RNA-binding sites in protein, but its inverse problem (i.e., predicting protein-binding sites in RNA) has received much less attention. Furthermore, most methods that predict RNA-binding sites in protein do not consider interaction partners of a protein. This paper presents a web server called PRIdictor (Protein–RNA Interaction predictor) which predicts mutual binding sites in RNA and protein at the nucleotide- and residue-level resolutions from their sequences. PRIdictor can be used as a web-based application or web service at http://bclab.inha.ac.kr/pridictor.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:0303-2647
1872-8324
DOI:10.1016/j.biosystems.2015.10.004