Can Mean Platelet Volume be a New Risk Factor in Portal Venous Thrombosis?

• Published in: Clinical and applied thrombosis/hemostasis Vol. 19; no. 4; pp. 433 - 436
• Main Authors: Aliosmanoglu, Ibrahim, Gul, Mesut, Oguz, Abdullah, Basol, Omer, Uslukaya, Omer, Keles, Celalettin
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.07.2013; SAGE PUBLICATIONS, INC
• Subjects: Adult; Female; Health risk assessment; Humans; Male; Mean Platelet Volume - methods; Middle Aged; Risk Factors; ROC Curve; Thrombosis; Venous Thrombosis - blood; Venous Thrombosis - pathology; portal venous thrombosis; mean platelet volume; etiology
• ISSN: 1076-0296; 1938-2723
• DOI: 10.1177/1076029612464903

Background: The aim of this study was to discuss the possibility of mean platelet volume (MPV) being a new risk factor in the etiology of portal venous thrombosis (PVT). Methods: Study participants were categorized into 2 different groups: group I, control group (n = 35) and group II, PVT group (n = 34). Demographic data and MPV values were recorded retrospectively. Results: No differences were determined between the 2 groups regarding hypertension, diabetes mellitus, and smoking (P > .05). The average hemoglobin levels were 10.8 ± 2.1 in group II and 14.0 ± 1.7 in group I (P < .001). Although the MPV levels of group II patients were 8.2 ± 0.52, the average level in group I was determined as 7.8 ± 0.62 (P = .012). In the performed receiver–operating characteristic (ROC) analysis, the cutoff value for patients with PVT for MPV was determined as 7.9 (area under curve: 0.674), sensitivity as 70.6%, and specificity as 65.7% (P = .013). Conclusion: The current study shows that MPV is significantly higher in patients with PVT than in the control group.