Bayesian semiparametric modeling for HIV longitudinal data with censoring and skewness

• Published in: Statistical methods in medical research Vol. 28; no. 5; p. 1457
• Main Authors: Castro, Luis M, Wang, Wan-Lun, Lachos, Victor H, Inácio de Carvalho, Vanda, Bayes, Cristian L
• Format: Journal Article
• Language: English
• Published: England 01.05.2019
• Subjects: semiparametric regression; skewness; mixed-effects models; Censored longitudinal data; HIV viral load

In biomedical studies, the analysis of longitudinal data based on Gaussian assumptions is common practice. Nevertheless, more often than not, the observed responses are naturally skewed, rendering the use of symmetric mixed effects models inadequate. In addition, it is also common in clinical assays...