Amiodarone pulmonary toxicity presenting as bilateral exudative pleural effusions

Therapy with the antiarrhythmic drug amiodarone has been associated with drug-related side effects. In addition to pulmonary fibrosing alveolitis, anecdotal reports have alluded to incidental pleural involvement associated with amiodarone. We describe an unusual manifestation of amiodarone-induced p...

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Bibliographic Details
Published inChest Vol. 92; no. 1; p. 179
Main Authors Gonzalez-Rothi, R J, Hannan, S E, Hood, C I, Franzini, D A
Format Journal Article
LanguageEnglish
Published United States 01.07.1987
Subjects
Amiodarone - toxicity
Humans
Lung - drug effects
Lung - pathology
Male
Middle Aged
Pleura - drug effects
Pleura - pathology
Pleural Effusion - chemically induced
Pleurisy - chemically induced
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Summary:Therapy with the antiarrhythmic drug amiodarone has been associated with drug-related side effects. In addition to pulmonary fibrosing alveolitis, anecdotal reports have alluded to incidental pleural involvement associated with amiodarone. We describe an unusual manifestation of amiodarone-induced pulmonary toxicity in a patient with bilateral exudative pleural effusions and toxic involvement of other organs. We review amiodarone-associated pleural reactions reported in the literature.
ISSN:0012-3692
1931-3543
DOI:10.1378/chest.92.1.179