Are antidepressant drugs efficacious in the treatment of fibromyalgia?

• Published in: The Western journal of medicine Vol. 175; no. 5; p. 314
• Main Authors: O'Malley, PG, Balden, E, Tomkins, G, Santoro, J, Kroenke, K, Jackson, JL
• Format: Journal Article
• Language: English
• Published: United States Copyright 2001 BMJ Publishing Group 01.11.2001; BMJ Publishing Group LTD
• Subjects: Antidepressants; Antidepressive Agents - therapeutic use; Confidence intervals; Drugs; Fibromyalgia; Fibromyalgia - drug therapy; Humans; Studies; Treatment Outcome

Trials assessed the efficacy of 3 classes of antidepressant drugs: tricyclic antidepressants (8 trials of amitriptyline hydrochloride, 1 of clomipramine hydrochloride, and 1 of maprotiline hydrochloride), S-adenosyl-1-methionine (2 trials), and selective serotonin reuptake inhibitors (2 of fluoxetin...