Are antidepressant drugs efficacious in the treatment of fibromyalgia?

Trials assessed the efficacy of 3 classes of antidepressant drugs: tricyclic antidepressants (8 trials of amitriptyline hydrochloride, 1 of clomipramine hydrochloride, and 1 of maprotiline hydrochloride), S-adenosyl-1-methionine (2 trials), and selective serotonin reuptake inhibitors (2 of fluoxetin...

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Bibliographic Details
Published inThe Western journal of medicine Vol. 175; no. 5; p. 314
Main Authors O'Malley, PG, Balden, E, Tomkins, G, Santoro, J, Kroenke, K, Jackson, JL
Format Journal Article
LanguageEnglish
Published United States Copyright 2001 BMJ Publishing Group 01.11.2001
BMJ Publishing Group LTD
Subjects
Antidepressants
Antidepressive Agents - therapeutic use
Confidence intervals
Drugs
Fibromyalgia
Fibromyalgia - drug therapy
Humans
Studies
Treatment Outcome
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Summary:Trials assessed the efficacy of 3 classes of antidepressant drugs: tricyclic antidepressants (8 trials of amitriptyline hydrochloride, 1 of clomipramine hydrochloride, and 1 of maprotiline hydrochloride), S-adenosyl-1-methionine (2 trials), and selective serotonin reuptake inhibitors (2 of fluoxetine hydrochloride and 1 of citalopram hydrobromide).
Bibliography:Corresponding author of original paper: P G O'Malley Department of Medicine Walter Reed Army Medical Center 6900 Georgia Ave Washington, DC 20307-5001
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Related-article-href:11694476
Treatment of fibromyalgia with antidepressants: a meta-analysis. J Gen Intern Med 2000;15:659-66611029681Competing interests: None declaredFunding: MacArthur Foundation Initiative on Depression in Primary CareThis digest and commentary appeared in Evidence-Based Medicine 2001;6:77
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Treatment of fibromyalgia with antidepressants: a meta-analysis. J Gen Intern Med 2000;15:659-66611029681
Competing interests: None declared
This digest and commentary appeared in Evidence-Based Medicine 2001;6:77
Funding: MacArthur Foundation Initiative on Depression in Primary Care
ISSN:0093-0415
1476-2978
DOI:10.1136/ewjm.175.5.314