Gravimetric Method for in Vitro Calibration of Skin Hydration Measurements

A novel method for in vitro calibration of skin hydration measurements is presented. The method combines gravimetric and electrical measurements and reveals an exponential dependency of measured electrical susceptance to absolute water content in the epidermal stratum corneum. The results also show...

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Published inIEEE transactions on biomedical engineering Vol. 55; no. 2; pp. 728 - 732
Main Authors Martinsen, Ørjan G., Grimnes, Sverre, Nilsen, Jon K., Tronstad, Christian, Jang, Wooyoung, Kim, Hongsig, Shin, Kunsoo, Naderi, Majid, Thielmann, Frank
Format Journal Article
LanguageEnglish
Published United States IEEE 01.02.2008
The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subjects
Absorption
Adult
Bioelectric phenomena
Biomedical measurements
Body Water - metabolism
Calibration
Clinical diagnosis
Electric Conductivity
Electric variables measurement
Epidermis
Frequency measurement
Humans
Humidity
In vitro
Male
Norway
Physics
Skin
Skin Absorption - physiology
Skin Tests - methods
Skin Tests - standards
stratum corneum
water
Water - analysis
Norway
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Summary:A novel method for in vitro calibration of skin hydration measurements is presented. The method combines gravimetric and electrical measurements and reveals an exponential dependency of measured electrical susceptance to absolute water content in the epidermal stratum corneum. The results also show that absorption of water into the stratum corneum exhibits three different phases with significant differences in absorption time constant. These phases probably correspond to bound, loosely bound, and bulk water.
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ISSN:0018-9294
1558-2531
DOI:10.1109/TBME.2007.912651