Solid-phase synthesis: a paradigm shift
A personal review by the first graduate student of Professor R. Bruce Merrifield of the evolution of solid‐phase synthesis and its acceptance by various subsets of the chemistry community. Solid‐phase synthesis, as currently practised in the synthesis of biopolymers, combinatorial solid‐phase organi...
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Published in | Journal of peptide science Vol. 9; no. 9; pp. 534 - 544 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
Chichester, UK
John Wiley & Sons, Ltd
01.09.2003
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Subjects | |
Online Access | Get full text |
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Summary: | A personal review by the first graduate student of Professor R. Bruce Merrifield of the evolution of solid‐phase synthesis and its acceptance by various subsets of the chemistry community. Solid‐phase synthesis, as currently practised in the synthesis of biopolymers, combinatorial solid‐phase organic chemistry, synthesis of natural products, catalyst selection, chemical ligation and materials development, has proven a paradigm shift for the chemistry community. Copyright © 2003 European Peptide Society and John Wiley & Sons, Ltd. |
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Bibliography: | ark:/67375/WNG-B1W7MDG0-D istex:38B335982CABE48658C04CB67F0C41003DA7B613 ArticleID:PSC478 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-1 ObjectType-Feature-3 |
ISSN: | 1075-2617 1099-1387 |
DOI: | 10.1002/psc.478 |