Aspergillus fumigatus infection of the optic nerve with mycotic arteritis of cerebral vessels

A 56-year-old Caucasian male, with no obvious immune deficit or systemic disease, presented with unilateral loss of vision due to A. fumigatus infection involving the right optic nerve. There was no proptosis. Despite fungal chemotherapy he developed central nervous system involvement with mycotic a...

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Bibliographic Details
Published inHistopathology Vol. 6; no. 2; p. 227
Main Authors Fernando, S S, Lauer, C S
Format Journal Article
LanguageEnglish
Published England 01.03.1982
Subjects
Arteritis - pathology
Aspergillosis - pathology
Aspergillus fumigatus
Cerebral Arteries - pathology
Humans
Male
Middle Aged
Optic Nerve - pathology
Optic Nerve Diseases - pathology
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Summary:A 56-year-old Caucasian male, with no obvious immune deficit or systemic disease, presented with unilateral loss of vision due to A. fumigatus infection involving the right optic nerve. There was no proptosis. Despite fungal chemotherapy he developed central nervous system involvement with mycotic arteritis of the branches of the right middle cerebral artery, temporal lobe infarction and rupture of a mycotic aneurysm of the right internal carotid artery, and died. Review of the literature concerning orbital Aspergillus infection showed both this form of presentation and a rapidly fatal course to be unusual.
ISSN:0309-0167
DOI:10.1111/j.1365-2559.1982.tb02717.x