Clinical Practice Guidelines for Improving Outcomes in Sepsis
Sepsis is a common medical condition resulting from an infectious stimulus with a variable inflammatory response leading to a spectrum of clinical conditions from mild constitutional symptoms to varying degrees of organ dysfunction and death. The understanding of the patho-physiology of sepsis has l...
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| Published in | Heart, lung & circulation Vol. 17; pp. S26 - S31 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Australia
Elsevier B.V
2008
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| Subjects | |
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| Abstract | Sepsis is a common medical condition resulting from an infectious stimulus with a variable inflammatory response leading to a spectrum of clinical conditions from mild constitutional symptoms to varying degrees of organ dysfunction and death. The understanding of the patho-physiology of sepsis has lead to better treatment modalities and whilst sepsis is an increasingly more common condition world wide, the mortality from sepsis is nevertheless falling. Treatment algorithms have been promulgated over the years and levels of evidence for these have varied. This review will focus on the early management issues recently updated and released by a multi-national panel of experts based on best evidence, aimed at reducing sepsis related mortality by 25%. |
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| AbstractList | Sepsis is a common medical condition resulting from an infectious stimulus with a variable inflammatory response leading to a spectrum of clinical conditions from mild constitutional symptoms to varying degrees of organ dysfunction and death. The understanding of the patho-physiology of sepsis has lead to better treatment modalities and whilst sepsis is an increasingly more common condition world wide, the mortality from sepsis is nevertheless falling. Treatment algorithms have been promulgated over the years and levels of evidence for these have varied. This review will focus on the early management issues recently updated and released by a multi-national panel of experts based on best evidence, aimed at reducing sepsis related mortality by 25%. |
| Author | Ihle, Benno U., MD, FJFICM FRACP |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/18964253$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1016_j_jen_2010_06_020 crossref_primary_10_1111_evj_13198 crossref_primary_10_1017_cem_2014_77 crossref_primary_10_1016_j_cyto_2010_09_010 crossref_primary_10_1111_j_1549_8719_2010_00080_x |
| Cites_doi | 10.1056/NEJMoa067373 10.1161/01.CIR.0000066692.71008.BB 10.1097/00003246-199904000-00025 10.1378/chest.129.1.174 10.1097/00003246-199804000-00010 10.1056/NEJMoa050935 10.1056/NEJMoa022139 10.1001/jama.288.7.862 10.1001/jama.274.12.968 10.1097/01.CCM.0000063046.82359.4A 10.1097/01.CCM.0000217961.75225.E9 10.1136/bmj.328.7454.1490 10.1007/s00134-004-2157-0 10.1007/BF01740762 10.1007/BF01705408 10.1056/NEJM200103083441001 10.1186/cc3927 10.1136/ebm.11.1.2-a 10.1097/01.CCM.0000298158.12101.41 10.1097/00003246-200107000-00002 10.1056/NEJMoa071366 10.1128/JCM.36.1.105-109.1998 10.1056/NEJMoa010307 10.1097/01.CCM.0000085141.75513.2B 10.1016/S0140-6736(00)03495-4 10.1186/cc3909 |
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| SubjectTerms | Algorithms Cardiovascular EBM Humans Practice Guidelines as Topic Sepsis Sepsis - mortality Sepsis - pathology Sepsis - physiopathology Sepsis - therapy Septic shock Vasopressors |
| Title | Clinical Practice Guidelines for Improving Outcomes in Sepsis |
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