Clinical Practice Guidelines for Improving Outcomes in Sepsis

Sepsis is a common medical condition resulting from an infectious stimulus with a variable inflammatory response leading to a spectrum of clinical conditions from mild constitutional symptoms to varying degrees of organ dysfunction and death. The understanding of the patho-physiology of sepsis has l...

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Bibliographic Details
Published inHeart, lung & circulation Vol. 17; pp. S26 - S31
Main Author Ihle, Benno U., MD, FJFICM FRACP
Format Journal Article
LanguageEnglish
Published Australia Elsevier B.V 2008
Subjects
Algorithms
Cardiovascular
EBM
Humans
Practice Guidelines as Topic
Sepsis
Sepsis - mortality
Sepsis - pathology
Sepsis - physiopathology
Sepsis - therapy
Septic shock
Vasopressors
EBM
Sepsis
Septic shock
Vasopressors
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Summary:Sepsis is a common medical condition resulting from an infectious stimulus with a variable inflammatory response leading to a spectrum of clinical conditions from mild constitutional symptoms to varying degrees of organ dysfunction and death. The understanding of the patho-physiology of sepsis has lead to better treatment modalities and whilst sepsis is an increasingly more common condition world wide, the mortality from sepsis is nevertheless falling. Treatment algorithms have been promulgated over the years and levels of evidence for these have varied. This review will focus on the early management issues recently updated and released by a multi-national panel of experts based on best evidence, aimed at reducing sepsis related mortality by 25%.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1443-9506
1444-2892
DOI:10.1016/j.hlc.2008.08.005