WHO CNS5 2021 classification of gliomas: a practical review and road signs for diagnosing pathologists and proper patho-clinical and neuro-oncological cooperation

The 5th edition of World Health Organization (WHO) Central Nervous System (CNS) tumours classification has transformed the pathological diagnosis of gliomas from purely histological to the multilayered integrated one with molecular biomarkers necessary for proper classification, risk stratification,...

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Published inFolia neuropathologica Vol. 60; no. 2; pp. 137 - 152
Main Authors Sejda, Aleksandra, Grajkowska, Wiesława, Trubicka, Joanna, Szutowicz, Ewa, Wojdacz, Tomasz, Kloc, Wojciech, Iżycka-Świeszewska, Ewa
Format Journal Article
LanguageEnglish
Published Warsaw Termedia sp. z o.o 01.01.2022
Termedia Publishing House
Subjects
5th edition
Brain tumors
Central nervous system
Classification
Glioma
gliomas
neuropathology
Oncology
who
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Summary:The 5th edition of World Health Organization (WHO) Central Nervous System (CNS) tumours classification has transformed the pathological diagnosis of gliomas from purely histological to the multilayered integrated one with molecular biomarkers necessary for proper classification, risk stratification, and prognostic-predictive clinical purposes. Because of deep and important changes in taxonomy and diagnostic approach to gliomas, this manuscript is a review of WHO CNS classification 5th edition with general testing guidance for pathologists and clinicians working in neuro-oncology.
ISSN:1641-4640
1509-572X
DOI:10.5114/fn.2022.118183